Jenny Without Most of Her CoatI spent some time volunteering at a ferret shelter. I’ve owned ferrets for a number of years, and I had some time on my hands since I had just moved to the area. I volunteered to clean cages- as you can imagine with over 100 of the little guys it was quite a job, and had to be done three times a week. Anyway, during the course of changing the cages I got to handle quite a lot of the hobs and jills (male and female ferrets respectively), and it was certainly the high point of the experience. There was one ferret in particular who took a liking to me- her name was Jenny. Jenny was a special little girl in a number of ways, not the least of which was that she was a solitary ferret. Most ferrets prefer the company of other ferrets- a rare few prefer to be alone, or to be with humans. Four-year-old Jenny had been at the shelter for about six months since her previous owner had surrendered her because he found out she was sick- Jenny had Adrenal Disease.

Unfortunately this is far too common, many people adopt a ferret without knowing that many of our furry friends will at some point in their lives develop some serious medical conditions. One of these conditions, Adrenal Disease, is estimated to affect over 50% (some say up to 70%) of Americans Ferrets, with the majority of them being female (70% according to Dr. Williams, DVM). Adrenal disease is caused when lesions or tumors form on one or both of the adrenal glands. Typically the disease manifests itself between three and four years of age, but can happen at any time after the first year of life. The symptoms usually begin with hair loss (alopecia) on the tail, and then it works its way forward until there is just a little hair left on the neck, head, and feet. In females, the vulva will usually swell. Sometimes, you will see increased scratching, and a loss of energy. Some ferrets will drink and urinate much more than usual, develop a pot belly, anemia, or show marked weight loss. If you see these symptoms, it’s time for a visit to your vet.

The primary treatment for adrenal disease is removal of the afflicted adrenal gland. For some unknown reason the left gland accounts for the majority (over 60%) of problems. This is good news as the right adrenal is closer to several major blood vessels and is a more involved surgery. When both glands are affected, the veterinarian will usually leave a small portion of the right gland in place to continue to produce hormones and other necessary secretions. If your ferret is very old or sick, the veterinarian may prescribe medication to control (but not cure) Adrenal Disease. There’s an oral medication (Lysodren) which is given every three days for life, or monthly shots of Lupron.

Ferrets who undergo surgery may make a full recovery and live their normal lifespan (six to ten years). Ferrets without surgery or treatment may regrow their hair, but they will not get better. Untreated Adrenal Disease will continue to deteriorate your ferret’s quality of life, and they will become listless and loose muscle tone until they eventually die sooner than their natural lifespan- typically within two years. Part of being a responsible ferret owner is to make sure you get your ferret the medical care it needs.Jenny

I ended up adopting Jenny and getting her the needed surgery. Depending upon your vet this typically costs between $300 and $500- it’s a good idea to plan for this expense early with a ferret savings account. Jenny recovered from the surgery beautifully, and was a wonderful pet until she passed on three years later, she more than repaid me in love and laughter.

Tags: Ferret Adrenal Disease

"Ferret Adrenal Disease – What a Ferret Owner Should Know About a Bald Ferret" by Carpet Shark was published on April 11th, 2008 and is listed in Ferret Care.

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Comments on "Ferret Adrenal Disease – What a Ferret Owner Should Know About a Bald Ferret": 14 Comments

  1. Ferox wrote,

    I haven’t yet been taught about Ferret Adrenal disease, but it sounds very similar to Cushings Disease in dogs.

  2. Carpet Shark wrote,

    Hiya Doc-

    Here’s a little more technical detail from a vet you may want to look over for more detail:
    Ferret Adrenal Disease

  3. Elyzium wrote,

    Many thanks for your information,
    My male(n) 4yr old ferret has shed dramatically in the last few days & with the information gleaned from your site I now know which blood tests will give me conclusive results.
    (I am very lucky to have worked in a vet lab and have a biochemistry machine at my disposal, plus an excellent team of vets underneath the lab.)
    Kindest regards from the U.K.

  4. Carpet Shark wrote,

    Hi Elyzium-

    Yes, sounds like it’s time for some tests. Know that hair loss doesn’t automatically mean it’s adrenal disease- there could be other conditions causing the hair loss and the vet visit and bloodwork is the only way to know for sure. Hope your furkid is feeling better soon, and worse case montly luprin shots aren’t that bad- they worked out fine for Jenny. Thanks for being a great pet parent and taking the time to take care of you ferret!

  5. Teresa wrote,

    Although this is an older article, coming across is gives me some information that I was looking for. I have 6 ferrets, 4 of which I adopted from a shelter. The smallest, is barely bigger than a baby ferret (she was left in her cage, without food, in 2 inches of feces before she was brought to the shelter). She had always had coarse, and thin hair, but never balding. Its finally soft, yet it’s thinning out in the shoulders to where I see her pink skin underneath. I noticed a week ago her vulva is swollen. I really had not noticed hair loss before I noticed the swelling and looked it up.

    I have owned several, several, several ferrets throughout the years and this could be my first adrenal. Hopefully everything goes well at the vet tomorrow.

    Thanks for the info :)

  6. Carpet Shark wrote,

    Glad we could help Teresa, keep us up to date on the vet and we’re crossing our fingers for you and your little one.

  7. Ferret Pet Insurance | Laughing Ferret wrote,

    [...] they cover, particularly the most costly medical expenses I’ve seen with my ferrets over the years, Ferret Adrenal Disease and Insulinoma. Here’s what their customer service had to say: Thank you for contacting VPI Pet [...]

  8. Kamila wrote,

    My vet told me the surgery was about $2000!

  9. Carpet Shark wrote,

    Kamila, find another vet, ideally one that specializes in exotics. Jenny’s surgery was about $400. Certainly not cheap, but $2000 is very high.

  10. MICHELE wrote,

    where can i find resonable and trustworthy vet care for any of theese serious surgergies in oceancounty nj or near ocean county?

  11. Carpet Shark wrote,

    Hi Michele-

    I’d do a search for local ferret shelters and see what vet they use. If you don’t have shelters in the area, you can call the Humane Society and see what they do with surrendered ferrets- those folks will usually have a good vet. Finally as a last resort you could call the vets in your area and ask about their experience. Usually if you find a vet that specializes in exotics, they are more likely to be ferret knowledgeable…

  12. Gina wrote,

    My ferret was diagnosed with adrenal disease today. After the surgery, ultrasound, xray , and all of the other “necessary” tests, my total would be $2300. I could not afford that so I told the vet I would come back. I am in NY. Can anyone recommend a place to go that I could have this surgery done for under $500. I will travel.

  13. Mary wrote,

    First off, thanks for the info!
    My 5 year old male recently lost all of the hair on his tail. I did some research and i came to the conclusion that hair loss in the tail is normal. And luckily, a few weeks later it all came back. Now, he has lost all the hair on his back, and his hind legs. He also has one dark spot near his neck, and scratches a lot. After reading your info i’ve also realized that he has been urinating an unusually large amount. Gathering all of this, i find that he has adrenal gland disease.

  14. Carpet Shark wrote,

    Hi Mary-

    Glad we could help, but of course this article is no substitute for a vet diagnosis. There are other things than can cause hair loss, be sure to have your doc confirm, and then they can help you with a course of treatment.

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